Produced in Norway, Best DHA 500 from Calamari supplies highly concentrated omega-3 DHA (DocosaHexaenoic Acid), prepared from sustainably harvested squid. DHA is the most clinically proven of all the omega-3 fatty acid nutrients. Human metabolic capacity to make DHA is very limited so the bulk of our DHA must come from the diet. Experts agree that DHA is a nutrient essential for health.
DHA’s fundamental importance for health comes mainly from being a building block for the cell membrane systems that drive life’s most important processes. Simplistically, these are thin molecular sheets that house the majority of the proteins which power metabolism. DHA’s presence has a fluidising effect on the membranes, which “frees up” the proteins for their mobile, dynamic activities.
The DHA in cell membranes also is metabolically transformed to a variety of highly potent “docosanoid” molecules (protectins, resolvins, maresins, and others), that have numerous regulatory actions. The docosanoids help manage healthy inflammatory responses, may help support natural tissue generation, and other immune related processes, and generally help protect the cells and tissues against damage.
EPA (EicosaPentaenoic Acid) coexists with DHA in fish oils. It is a simpler omega-3 fatty acid than DHA and far less abundant in cell membranes. But EPA can compete against DHA for space in cell membranes, potentially “crowding out” DHA and blocking its vital actions. DHA, in contrast, does not crowd EPA out of membranes and even can be readily converted to EPA as needed. The evidence therefore favors supplementing with DHA in great excess over EPA, to ensure that sufficient DHA will actually reach the membranes of cells in the brain, eyes, heart, blood vessels, liver, immune system, and other organs.