What is andrographis?

Andrographis (Andrographis paniculata) is a herbaceous plant native to South and Southeast Asia. It has been used for centuries in Ayurvedic and Traditional Chinese Medicine.

It is known as the “king of bitters”, reflecting its intensely bitter taste. The whole plant has traditional medicinal uses, although supplements usually contain standardised leaves and aerial parts.

Its main active compound is andrographolide, a bitter diterpene lactone. Researchers have studied andrographolide for its potential immune-modulating and anti-inflammatory properties.

Immune support and seasonal wellness

Andrographis is widely used to support your immune system, particularly during autumn and winter. Research into standardised andrographis extracts has explored their effects on common upper respiratory symptoms.

Some studies have reported improvements in symptom relief and recovery time when supplementation begins at the first signs of symptoms. Andrographis is also considered an immunomodulator. Rather than simply stimulating your immune system, it may help support a balanced immune response.

Anti-inflammatory and antioxidant properties

Beyond immune support, laboratory research suggests that andrographolide has anti-inflammatory properties. It acts on several pathways involved in your body’s inflammatory response. This makes andrographis interesting for supporting a healthy inflammatory balance.

Andrographis also provides antioxidant support by helping neutralise free radicals. These can form during normal immune activity and metabolic processes. In Ayurveda, andrographis is also used as a liver tonic. Emerging research is exploring its potential role in supporting healthy liver function and detoxification.

Using andrographis

Andrographis is best taken as a standardised extract for consistent potency. Look for products that specify their andrographolide content, ideally at least 10%.

It is commonly used short term when seasonal challenges begin. You can also use it preventatively during periods when you are more likely to face seasonal challenges. Some practitioners recommend lower doses through the winter months.

Capsules and tablets are generally easier to take than tinctures because of andrographis’s intensely bitter taste. Avoid andrographis during pregnancy. If you take blood thinning medication, seek guidance before use.